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HGWD modified Sirt1/NF-κB/NLRP3 pathway in the hippocampus of MCAO rats. (A) Representative western blot bands of NLRP3, ASC and Cleaved Caspase-1 in each group. (B–D) The quantitative analysis of NLRP3, ASC and Cleaved Caspase-1 protein expression. (E) Representative western blot bands of Sirt1 and p-NF-κB in each group. (F, G) The quantitative analysis of Sirt1 and p-NF-κB protein expression. ##P < 0.01 vs. control group; *P< 0.05, **P< 0.01 vs. model group.
