TABLE 4.
Subgroup analysis of different doses of H101.
| H101 (n = 467) | H101+ chemotherapy (n = 176) | |||||||
|---|---|---|---|---|---|---|---|---|
| Response (n, %) | 0.5 mL (n = 80) | 1.0 mL (n = 155) | 1.5 mL (n = 116) | 2.0 mL (n = 116) | 0.5 mL (n = 35) | 1.0 mL (n = 51) | 1.5 mL (n = 45) | 2.0 mL (n = 45) |
| PR | 53 (66.2) | 85 (54.8) | 73 (62.9) | 71 (61.2) | 20 (57.1) | 29 (56.9) | 29 (64.4) | 28 (62.2) |
| NC | 24 (30.0) | 69 (44.5) | 40 (34.5) | 43 (37.1) | 15 (42.9) | 22 (43.1) | 16 (35.6) | 16 (35.6) |
| PD | 3 (3.8) | 1 (0.7) | 3 (2.6) | 2 (1.7) | 0 (0) | 0 (0) | 0 (0) | 1 (2.2) |
| ORR | 53 (66.2) | 85 (54.8) | 73 (62.9) | 71 (61.2) | 20 (57.1) | 29 (56.9) | 29 (64.4) | 2 (62.2) |
Abbreviations: NC, remission not obvious; ORR, overall remission rate; PD, progression; PR, partial remission.