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. 2023 Oct 25;14:6769. doi: 10.1038/s41467-023-42247-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Solid lines indicate a positive correlation coefficient between disease metadata and small molecules; dotted lines indicate a negative correlation coefficient between disease metadata and small molecules. Correlation line colors relate to the specific correlated metadata category. Small molecule box colors indicate feature restoration status: green for features restored by combination treatment, red for features restored by BNZ treatment, blue for features restored by both treatments, and gray for features not restored by any treatment. Note the greater number of not-restored features correlated to the metadata. RA right atrium, LA left atrium, RVT right ventricle top, RVB right ventricle bottom, LVT left ventricle top, LVB left ventricle bottom, DPI days post-infection. N = 15 mice per group and per position. Source data are provided as a Source Data file.