Table 1.

Image perturbation, preprocessing, and radiomic feature extraction parameters.

Pixel value offset	0
Resample pixel size (mm)	[1, 1, 1]
Image/mask interpolation algorithm	B-spline
Mask partial volume threshold	0.5
Interpolation grid alignment	Align grid origins
Translation distances (pixel)	[0.0, 0.2, 0.4, 0.6, 0.8]
Rotation angles (degree)	[− 5, 0, 5]
Rotation axis	Mask bounding box center, axial direction
Contour randomization smoothing sigma (mm)	[10, 10, 10]
Contour randomization intensity (mm)	[1, 1, 1]
Perturbation times	40
Image discretization bin number	32
Image filters	Unfiltered, Laplacian-of-Gaussian (3D), Wavelet
Kernel size of Laplacian-of-Gaussian filter (mm)	[1, 2, 3, 4, 5]
Wavelet filter starting level	0
Wavelet filter total level	1
Wavelet filter type	Coilf1
Wavelet filter decompositions	[LLL, HLL, LHL, LLH, LHH, HLH, HHL, HHH]
Feature class	Shape, firstorder, glcm, glrlm, glszm, gldm, ngtdm