Table 1.

Colonoscopy Surveillance Recommendations for Individuals with Germline Variants.

Syndrome	Family history of CRC	Age to begin surveillance (years)	Surveillance interval (years)
No mutation	No	50	10
	Yes	40*	5-10
Lynch syndrome	N/A	20-25	1-2
Familial adenomatous polyposis	N/A	10-15	1-3
MUTYH-associated polyposis	N/A	18-20	1-3
Juvenile polyposis	N/A	12-15	1-2
Peutz-Jeghers syndrome	N/A	Baseline: 8 Routine: 18	1-3
Cowden syndrome	N/A	15	2

*40 years old or 10 years before the age of the youngest first-degree relative diagnosed with CRC.

CRC, colorectal cancer