TABLE 1.
Particle size distribution of Amphocil in various media measured by photon correlation spectroscopy
| Formulationa | Amt (%) | Mean size (nm) | SD size (nm) |
|---|---|---|---|
| DDW | 100 | 122 | 24 |
| 5% EtOH in DDW | 2 | 18 | 3 |
| 90 | 167 | 53 | |
| 8 | 822 | 96 | |
| 10% EtOH in DDW | 80 | 205 | 83 |
| 20 | 1,270 | 150 | |
| 25% EtOH in DDW | 90 | 259 | 81 |
| 10 | 1,260 | 150 | |
| 5% glucose in DDW | 97 | 7.3 | 1 |
| 3 | 104 | 23 |
The reconstituted Amphocil dispersion contained 5 mg of AmB per ml in 5% glucose. EtOH, ethanol.