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. 2023 Sep 29;57(3):287–304. doi: 10.14744/SEMB.2023.06992

Table 3.

The 2023 Bethesda System for Reporting Thyroid Cytopathology (This table is established using The 2023 Bethesda System for Reporting Thyroid Cytopathology guideline (67))

Adult Pediatric
Diagnostic Category ROM
%Mean (min-max)
Usual Management ROM
%Mean (min-max)
Usual Management
Nondiagnostic Bethesda I %13 (5-20) Repeat FNA with ultrasound guidance %14 (0-33) Repeat FNA with ultrasound guidance
Benign Bethesda II %4 (2-7) Clinical and ultrasound follow-up %6 (0-27) Clinical and ultrasound follow-up
Atypia of undetermined significance Bethesda III %22 (13-30) Repeat FNA, molecular testing, lobectomy, surveillance %28 (11-54) Repeat FNA, lobectomy
Follicular Neoplasm Bethesda IV %30 (23-34) Molecular testing, diagnostic lobectomy %50 (%58-100) Surgical resection
Suspicious for malignancy Bethesda V %74 (67-83) Molecular testing, lobectomy or near-total thyroidectomy %81 (40-100) Surgical resection
Malignant Bethesda VI %97 (97-100) Lobectomy or near-total thyroidectomy %98 (86-100) Surgical resection