Table 1.
Reasons for patients receiving low-dose thrombolytic therapy
| Age (year) | Gender | Reasons for using low-dose treatment | Weight of patients (kg) | Recommended dose based on patients’ weight (mg) | Difference of dose (mg)* |
|---|---|---|---|---|---|
| 62 | M | Received one dose LMWH at another hospital (we learned during the IV-tPA treatment and stopped) | 60 | 54 | 4 |
| 53 | M | Admission at near the treatment window limit and neurological deterioration during the IV-tPA treatment | 74 | 66.6 | 16.6 |
| 87 | F | Renal failure (regular hemodialysis) | 80 | 72 | 22 |
| 66 | F | Admission at near the treatment window limit and resistant HT requiring IV antihypertensive therapy | 68 | 61.9 | 11.9 |
| 65 | M | Allergic reaction | 58 | 52.2 | 2.2 |
| 57 | M | The reason was not stated in patients’ medical reports | 86 | 77.4 | 27.4 |
| 62 | M | •Renal failure (regular hemodialysis) | 78 | 71.2 | 21.2 |
| 59 | M | Received one dose LMWH at another hospital (we learned during the IV-tPA treatment and stopped) | 78 | 71.2 | 21.2 |
| 69 | F | Admission at near the treatment window limit and resistant HT requiring IV antihypertensive therapy | 100 | 90 | 40 |
| 73 | M | •Received one dose LMWH and presence of several risk factors for bleeding complication | 72 | 64.8 | 14.8 |
| 91 | F | •Advanced age and presence of several risk factors for bleeding complication | 58 | 52.2 | 2.2 |
| 68 | M | Treatment could not be completed because of delirium | 80 | 72 | 22 |
| 53 | M | The reason was not stated in patients’ medical reports | 75 | 67.5 | 17.5 |
| 77 | F | Resistant HT requiring IV antihypertensive therapy | 80 | 72 | 22 |
| 75 | M | Resistant HT requiring IV antihypertensive therapy | 82 | 73.8 | 23.8 |
| 41 | M | Admission at near the treatment window limit and resistant HT requiring IV antihypertensive therapy | 62 | 55.8 | 5.8 |
| 74 | F | Resistant HT requiring IV Antihypertensive therapy | 70 | 63 | 13 |
| 76 | F | Resistant HT requiring IV Antihypertensive therapy | 74 | 66.6 | 15.6 |
| 81 | F | •Renal failure | 75 | 67.5 | 17.5 |
M: Male; F: Female; LMWH: Low molecular weighted heparin; HT: Hypertension; IV: Intravenous. All of the patients received IV rTPA at a total dose of 50 mg; *: Recommended treatment dose-received treatment dose; •: Patients initially scheduled for low-dose IV rTPA.