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. 2023 Sep 29;57(3):359–366. doi: 10.14744/SEMB.2023.51437

Table 1.

Reasons for patients receiving low-dose thrombolytic therapy

Age (year) Gender Reasons for using low-dose treatment Weight of patients (kg) Recommended dose based on patients’ weight (mg) Difference of
dose (mg)*
62 M Received one dose LMWH at another hospital (we learned during the IV-tPA treatment and stopped) 60 54 4
53 M Admission at near the treatment window limit and neurological deterioration during the IV-tPA treatment 74 66.6 16.6
87 F Renal failure (regular hemodialysis) 80 72 22
66 F Admission at near the treatment window limit and resistant HT requiring IV antihypertensive therapy 68 61.9 11.9
65 M Allergic reaction 58 52.2 2.2
57 M The reason was not stated in patients’ medical reports 86 77.4 27.4
62 M •Renal failure (regular hemodialysis) 78 71.2 21.2
59 M Received one dose LMWH at another hospital (we learned during the IV-tPA treatment and stopped) 78 71.2 21.2
69 F Admission at near the treatment window limit and resistant HT requiring IV antihypertensive therapy 100 90 40
73 M •Received one dose LMWH and presence of several risk factors for bleeding complication 72 64.8 14.8
91 F •Advanced age and presence of several risk factors for bleeding complication 58 52.2 2.2
68 M Treatment could not be completed because of delirium 80 72 22
53 M The reason was not stated in patients’ medical reports 75 67.5 17.5
77 F Resistant HT requiring IV antihypertensive therapy 80 72 22
75 M Resistant HT requiring IV antihypertensive therapy 82 73.8 23.8
41 M Admission at near the treatment window limit and resistant HT requiring IV antihypertensive therapy 62 55.8 5.8
74 F Resistant HT requiring IV Antihypertensive therapy 70 63 13
76 F Resistant HT requiring IV Antihypertensive therapy 74 66.6 15.6
81 F •Renal failure 75 67.5 17.5

M: Male; F: Female; LMWH: Low molecular weighted heparin; HT: Hypertension; IV: Intravenous. All of the patients received IV rTPA at a total dose of 50 mg; *: Recommended treatment dose-received treatment dose; •: Patients initially scheduled for low-dose IV rTPA.