Table 3.
Comparison of clinical and functional outcomes in low-dose vs. standard dose thrombolytic therapy groups
| Clinical outcomes | Low-dose, n=19, (17.4%) | Standard-dose, n=90, (82.6%) | Test statistic | Total, n=109 | P |
|---|---|---|---|---|---|
| ENI within 24 h, n (%) | 7 (36.8) | 26 (28.9) | 0.16 | 33 (30.3) | 0.68a |
| NIHSS (at 24 h post-treatment) | 8 (0–25)/50.61 | 10 (0–26)/ 55.93 | 771 | 9 (0–26) | 0.50b |
| aSIH, n (%) | 1 (5.3) | 12 (13.3) | - | 13 (11.9) | 0.45c |
| SIH, n (%) | 1 (5.3) | 3 (3.3) | - | 4 (3.7) | 0.54c |
| 3. month mRS ≤2, n (%) | 9 (47.4) | 47 (52.2) | 0 .00 | 56 (51.4) | 1a |
| Mortality, n (%) | 6 (31.6) | 20 (22.2) | - | 26 (23.9) | 0.38c |
aSIH: Asymptomatic ıntracerebral hemorrhage; ENI: Early neurological improvement; Min.: Minimum; Max.: Maximum; mRS: Modified rankin scale; NIHSS: The national ınstitutes of health stroke scale score; SIH: Symptomatic ıntracerebral hemorrhage; Data were expressed as median (minimum: maximum)/mean Rank and n (%); a: Continuity correction; b: Mann Whitney U-test; c: Fisher’s exact test