Figure 2. Kaplan-Meier Estimates of the Probability of Survival and Survival Without the Need for Assisted Ventilation During the First 28 Days After Randomization.

Successful extubation was defined as the patient being able to breathe unassisted and maintaining unassisted breathing until the end of the study period. Among those who died, the median days from randomization to death was 5.5 (IQR, 2.1-9.8; n = 30) in the sighs plus usual care group and 5.3 (IQR, 3.5-9.1; n = 46) in the usual care alone group. Among those who were successfully extubated, the median days from randomization to extubation was 6.4 (IQR, 1.9-12.9; n = 209) in the sighs plus usual care group and 6.8 (IQR, 2.8-13.2; n = 197) in the usual care alone group.