Table 3.
Comparative analyses for inflammatory factors levels pre-/post-therapy in all cohorts (x ± s)
| Cohort |
CRP (mg/L)
|
TNF-α (ng/L)
|
IL-6 (ng/L)
|
MCP-1 (ng/L)
|
||||
|
Pre-therapy
|
Post-therapy
|
Pre-therapy
|
Post-therapy
|
Pre-therapy
|
Post-therapy
|
Pre- therapy
|
Post-therapy
|
|
| Cohort A (n = 20) | 32.84 ± 3.90 | 17.14 ± 2.27a,b,c | 10.11 ± 1.74 | 2.62 ± 0.83a,b,c | 34.92 ± 2.31 | 15.27 ± 1.15a,b,c | 213.33 ± 14.91 | 122.91 ± 19.00a,b,c |
| Cohort B (n = 20) | 34.40 ± 4.67 | 19.99 ± 3.51a,c | 11.03 ± 1.99 | 3.79 ± 1.06a,c | 35.59 ± 1.59 | 18.88 ± 1.58a,c | 215.24 ± 19.15 | 150.74 ± 19.76a,c |
| Cohort C (n = 20) | 32.27 ± 2.78 | 25.16 ± 2.41a | 10.80 ± 2.06 | 5.35 ± 0.95a | 34.92 ± 3.09 | 23.43 ± 2.26a | 211.07 ± 16.46 | 167.83 ± 15.10a |
| F value | 1.636 | 42.566 | 1.227 | 41.469 | 0.526 | 112.506 | 0.303 | 31.482 |
| P value | 0.204 | < 0.001 | 0.301 | < 0.001 | 0.594 | < 0.001 | 0.740 | < 0.001 |
Indicated P < 0.05 when compared with the same cohort pre-therapy.
Indicated P < 0.05 when compared with cohort B.
Indicated P < 0.05 when compared with cohort C.
CRP: C-reactive protein; TNF-α: Tumor necrosis factor-alpha; IL-6: Interleukin-6; MCP-1: Monocyte chemoattractant protein-1.