TABLE 2.

NNRTI resistance-associated mutations and loviride resistance

Sample	Mutation(s) in RT sequences from:		IC50 (μM)	Log10 fold resistance
	Plasma	Recombinant virus
B701	K103N	NAa	0.475	1.12
B702	K103N	K103N	1.6506	2
B703	None	None	0.0187	0.04
B704	K103N	K103N	1.7026	2.01
B705	K103N, K238T	K103N, K238T	49.225	3.47
B706	K103N	K103N, P225P/L	2.09	2.1
B707	K103N	NA	1.3	1.9
B708	K103S	K103S	2.419	2.17
B709	K103N	NA	1.599	1.4
B710	None	None	0.0412	0.4
B711	V108I	NA	0.134	0.3
B712	K103N	K103N	3.7342	2.35
B714	K103S	K103N	0.9554	1.76
B715	None	None	0.1427	0.57
B716	K103N	K103N	0.9494	1.76
B717	K103N	K013N	1.6452	2
B718	K101E, K103K/N, E138A	K101E, K103K/N, E138A	8.996	2.74
B719	A98G	A98X, K238T	0.42	1.4
B720	K103N	NA	0.4352	1.05
B721	K103N	K103N	1.24	1.88
B723	Y181C	Y181C	9.2802	2.75
B724	K101Q	K101Q	0.29	1.26
B725	K103N	K103N, I108I/V	0.9846	1.78
B726	K103N	K103N	2.8346	2.24

^aNA, not applicable.