Table 1.
Patient Demographics.a
| Control (n = 50) | Skin invasion (n = 25) | Total (N = 75) | P value | |
|---|---|---|---|---|
| Age,b y | 63 (57-70) | 62 (58.25-69.5) | 63 (56.75-70) | |
| Sex | .607 | |||
| Men | 34 (68) | 17 (68) | 51 (68) | |
| Women | 16 (32) | 8 (32) | 24 (32) | |
| Margin | .158 | |||
| Positive | 6 (12) | 6 (24) | 12 (16) | |
| Negative | 44 (88) | 19 (76) | 63 (84) | |
| Site of primary tumor | — | |||
| Mucosal lip | 0 (0) | 5 (20) | 5 (6.7) | |
| Buccal mucosa | 4 (8) | 2 (8) | 6 (8) | |
| Upper alveolar ridge | 0 (0) | 0 (0) | 0 (0) | |
| Lower alveolar ridge | 15 (30) | 7 (28) | 22 (29.3) | |
| Retromolar trigone | 8 (16) | 1 (4) | 9 (12) | |
| Floor of mouth | 14 (28) | 10 (40) | 24 (32) | |
| Tongue | 9 (18) | 0 (0) | 9 (12) | |
| Hard palate | 0 (0) | 0 (0) | 0 (0) | |
| Pathologic N stage | .398 | |||
| N0 | 28 (56) | 10 (40) | 38 (50.7) | |
| N1 | 3 (6) | 1 (4) | 4 (5.3) | |
| N2 | 5 (10) | 2 (8) | 7 (9.3) | |
| N3 | 14 (28) | 12 (48) | 26 (34.7) | |
| Adjuvant treatment | .929 | |||
| None | 12 (24) | 8 (32) | 20 (26.7) | |
| Chemotherapy | 0 (0) | 0 (0) | 0 (0) | |
| Radiation therapy | 21 (42) | 8 (32) | 29 (38.7) | |
| Chemotherapy and radiation therapy | 13 (26) | 6 (24) | 19 (25.3) | |
| Chemotherapy and immunotherapy | 1 (2) | 1 (4) | 2 (2.7) | |
| Radiation therapy and immunotherapy | 2 (4) | 1 (4) | 3 (4) | |
| Chemotherapy, radiation therapy, and immunotherapy | 1 (2) | 1 (4) | 2 (2.7) | |
| Perineural invasion | .030c | |||
| Present | 21 (42) | 17 (68) | 38 (51) | |
| Absent | 29 (58) | 8 (32) | 37 (49) | |
| Extranodal extension | .151 | |||
| Yes | 33 (67) | 13 (52) | 46 (62) | |
| No | 16 (33) | 12 (48) | 28 (38) |
a
Values are presented as No. (%) unless noted otherwise.
b
Median (interquartile range).
c
P < .05.