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(A) 3D interaction of compound 18 (green) with site-1 in the PI3K complex (PDB: 3HNM). (B) 2D interaction of compound 18 (green) with site-1 in the PI3K complex. (C) 3D interaction of compound 5b (cyan) with site-1 in the PI3K complex (PDB: 3HNM). (D) 2D interaction of compound 18 (cyan) with site-1 in the PI3K complex.
