Table 1. Rf Values of Suvorexant (SUV) and IS Were Recorded Using Different Eluent Systems (Mean ± SD; n = 3).
Rf |
||
---|---|---|
eluent system | IS | SUV |
acetone/cyclohexane (90:10 v/v) | 0.18 ± 0.01 | 0.91 ± 0.03 |
acetone/cyclohexane (97.5:2.5 v/v) | 0.17 ± 0.01 | 0.90 ± 0.03 |
cyclohexane/ethyl acetate (90:10 v/v) | 0.15 ± 0.01 | 0.89 ± 0.02 |
cyclohexane/ethyl acetate (97.5:2.5 v/v) | 0.14 ± 0.01 | 0.88 ± 0.02 |
ethyl acetate/methanol (90:10 v/v) | 0.12 ± 0.01 | 0.87 ± 0.02 |
ethyl acetate/methanol (97.5:2.5 v/v) | 0.11 ± 0.01 | 0.86 ± 0.02 |
chloroform/methanol (90:10 v/v) | 0.10 ± 0.00 | 0.46 ± 0.01 |
chloroform/methanol (97.5:2.5 v/v) | 0.09 ± 0.00 | 0.45 ± 0.01 |