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. 2023 Oct 16;8(42):39928–39935. doi: 10.1021/acsomega.3c07123

Table 1. Rf Values of Suvorexant (SUV) and IS Were Recorded Using Different Eluent Systems (Mean ± SD; n = 3).

  Rf
eluent system IS SUV
acetone/cyclohexane (90:10 v/v) 0.18 ± 0.01 0.91 ± 0.03
acetone/cyclohexane (97.5:2.5 v/v) 0.17 ± 0.01 0.90 ± 0.03
cyclohexane/ethyl acetate (90:10 v/v) 0.15 ± 0.01 0.89 ± 0.02
cyclohexane/ethyl acetate (97.5:2.5 v/v) 0.14 ± 0.01 0.88 ± 0.02
ethyl acetate/methanol (90:10 v/v) 0.12 ± 0.01 0.87 ± 0.02
ethyl acetate/methanol (97.5:2.5 v/v) 0.11 ± 0.01 0.86 ± 0.02
chloroform/methanol (90:10 v/v) 0.10 ± 0.00 0.46 ± 0.01
chloroform/methanol (97.5:2.5 v/v) 0.09 ± 0.00 0.45 ± 0.01