Table 1.
General characteristics at baseline
| Parameters | All patients(n = 118) | ESI (cm2/m2) | P value | ||||
|---|---|---|---|---|---|---|---|
| <12.05 (n = 58) | ≥ 12.05 (n = 60) | ||||||
| Demographic | |||||||
| Age (years) | 42.9 ± 10.7 | 43.8 ± 11.8 | 42.2 ± 9.5 | 0.420 | |||
| Male, n (%) | 104(88.1) | 52(89.7) | 52(86.7) | 0.616 | |||
| ESI (cm2/m2) | 12.6 ± 3.8 | 11.3 ± 4.0 | 13.5 ± 3.4 | 0.026 | |||
| Laboratory indicators | |||||||
| Albumin (g/L) | 30.2 ± 4.4 | 29.1 ± 5.1 | 32.2 ± 6.7 | 0.069 | |||
| Globulin (g/L) | 25.9 ± 7.4 | 26.1 ± 8.1 | 25.7 ± 6.8 | 0.849 | |||
| Bilirubin (mg/dL) | 20.1 ± 7.7 | 21.0 ± 8.3 | 19.2 ± 7.1 | 0.377 | |||
| ALT (U/L) | 132(13-2329) | 153(94–349) | 117(38–496) | 0.423 | |||
| AST (U/L) | 166(47-1500) | 208(134–349) | 116(77–400) | 0.243 | |||
| GGT (U/L) | 64(15–231) | 63(45–95) | 68(37–103) | 0.846 | |||
| Creatinine (µmol/L) | 97.1 ± 17.0 | 98.6 ± 19.8 | 95.7 ± 14.3 | 0.526 | |||
| INR | 3.1 ± 0.5 | 2.1 ± 0.4 | 4.1 ± 0.6 | 0.172 | |||
| WBC (×109/L) | 7.0 ± 4.9 | 7.9 ± 6.4 | 6.2 ± 2.8 | 0.186 | |||
| Hemoglobin (g/L) | 119 ± 23 | 117 ± 24 | 120 ± 22 | 0.564 | |||
| Platelet count (×109/L) | 85 ± 42 | 76 ± 33 | 93 ± 48 | 0.125 | |||
| Serum ammonia (mmol/L) | 65.8 ± 22.4 | 69.1 ± 25.8 | 62.4 ± 18.2 | 0.030 | |||
| HBV DNA (log10 IU/ml) | 3.2 ± 2.2 | 3.0 ± 2.1 | 3.3 ± 2.3 | 0.643 | |||
| MELD | 27.4 ± 6.8 | 28.2 ± 8.7 | 26.6 ± 3.7 | 0.365 | |||
| MELD-Na | 30.4 ± 9.4 | 30.7 ± 7.9 | 30.2 ± 10.8 | 0.837 | |||
| Complications at baseline | |||||||
| Ascites, n (%) | 106(89.8) | 54(93.1) | 52(86.7) | 0.247 | |||
| SBP, n (%) | 25(21.2) | 18(31.0) | 7(11.7) | 0.010 | |||
| Kidney dysfunction, n (%) | 16(13.5) | 12(20.7) | 4(6.7) | 0.026 | |||
| Hepatic encephalopathy, n (%) | 13(11.0) | 10(17.2) | 3(5.0) | 0.034 | |||
| Respiratory infections, n (%) | 17(14.4) | 9(15.5) | 8(13.3) | 0.736 | |||
| Hyponatremia, n (%) | 50(42.4) | 26(44.8) | 24(40.0) | 0.596 | |||
| Other types of infection, n (%) | 19(16.1) | 10(17.2) | 9(15.0) | 0.741 | |||
Abbreviations. ESI: erector spine index, ALT: alanine transaminase, AST: aspartate transaminase, GGT: γ-glutamyl transferase, INR: international normalized ratio, WBC: white blood cell count, MELD: model for end-stage liver disease, MELD-Na: MELD-Sodium, SBP: spontaneous bacterial peritonitis