Table 1.
Q10-values | hi-PSC-CM | Dietrichs et al | Thomsen et al | Yoon et al | Rosol et al | Salinas et al | Weitz et al | Kim et al | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameter | APD90 | APD90c | QTc | QT | QTc | QT | QTc | QT | QTc | QT | QTc | QT | QTc | QT | QTc |
Mild hypothermia | 3.2 | 2.3 | 1.4 | 1.4 | 1.1 | 2.4 | 1.4 | 2.0 | 1.3 | 1.6–2.2 | 1.3–1.5 | 2.1 | 1.6 | 2.1 | 1.3 |
Moderate hypothermia | 2.9 | 2.3 | 1.2 | ||||||||||||
Severe hypothermia | 2.8 | 2.3 | 1.2 |
Data was derived from a literature search in PubMed for (therapeutic hypothermia) and (QT interval) and a search for (deep hypothermia) and (QT interval). Included papers had to report human, adult data from the last 10 years and report absolute QT or QTc. The search for deep hypothermia did not have to include data from the last 10 years. No case reports were included. Reference lists of included papers were screened for relevant papers. Thomsen et al. are estimated Q10-value by deriving approximate numbers from graphs