Table 1.

Data portals for quality control studies based on reference materials

	GIAB	HUPO-PSI	MAQC/SEQC	mQACC	Quartet	Sequin
Reference materials request	Links to NIST, Coriell, and PGP	No	No	No	Direct application	Direct application
Data availability	Links to FTP	No	Links to NCBI SRA and FTP	No	Direct download	No
Analysis tools	A package of hap.py and a web-based implementation of this tool in GA4GH Benchmarking app on precisionFDA	Dozens of packages for exchanging data formats, capturing molecular interactions, and reporting data quality	Example codes for benchmarking, a R package containing summarized read counts and exon-exon junctions	No	Online applications for analyzing and reporting the user-submit data quality	No
Data retrieval	No	No	No	No	Raw sequencing data or quantitative profiles, and structured metadata	No
Account requirement	Yes	No	No	No	Yes	Yes
Additional assistance	Connections to opportunities, e.g., workshops and collaborations	Controlled vocabularies, reporting guidelines for proteomics	Many types of tutorials	No	Interactive visualization	No