Fig. 3.

Microscopically, the tumor was composed of large polygonal cells arranged in a trabecular pattern separated by sinusoid-like blood spaces. a Tumor cells had enlarged and hyperchromatic nuclei with prominent nucleoli and abundant eosinophilic cytoplasm (H&E stain, ×100). Immunohistochemical staining of the tumor showed capillarization of the sinusoidal vessels (CD34 stain, ×100) (b), and strong and diffuse granular cytoplasmic staining (Hep Par 1 statin, ×100) (c). The histologic diagnosis was ectopic HCC of the trabecular type. Its histologic grade was consistent with Edmondson grade II. Nuclei are enlarged and hyperchromatic.