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. 2023 Feb 14;12(4):309–320. doi: 10.1159/000529636

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© 2023 The Author(s). Published by S. Karger AG, Basel

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Fig. 2. — OS and PFS (ITT). OS (a) and PFS (b) per RECIST v1.1 by BICR. a Based on the Cox regression model with Efron’s method for handling ties, with treatment as a covariate stratified by the same stratification factors for randomization, with small strata collapsed as prespecified in the statistical analysis plan. BICR, blinded independent central review; CI, confidence interval; HR, hazard ratio; ITT, intention to treat; PFS, progression-free survival; OS, overall survival; RECIST v1.1, Response Evaluation Criteria in Solid Tumors, version 1.1.