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. Author manuscript; available in PMC: 2023 Oct 26.
Published in final edited form as: Nat Genet. 2023 Sep 28;55(10):1651–1664. doi: 10.1038/s41588-023-01518-4

Figure 5 |. Immunofluorescence staining showing localization of ENPP1, IGFBP3, ARID5B and ADK in control and atherosclerotic human coronary arteries.

Figure 5 |

a,b, Transverse sections of healthy control (a) and atherosclerotic (b) human coronary arteries were stained for alpha-smooth muscle actin (α-SMA) (green), DAPI nuclei marker (blue), ENPP1/PC-1 (white), IGFBP3 (red), ARID5B (purple), and ADK (yellow). High levels of ENPP1/PC-1, IGFBP3, ARID5B, and ADK were observed in the neointimal layer of atherosclerotic diseased coronary arteries. Whole artery images were captured at 10× magnification and regions of interest were captured at 20×. Images are representative of n = 4 independent donors per group.