Figure 5. Differential response to IL-17A stimulation between non-PSC and PSC ECO by scRNA-seq.
A) Dot plots displaying pseudo bulk DEG between ECO treated with vehicle and IL-17A within each condition (PSC vs non-PSC). B) Dot plots displaying DEG between PSC and non-PSC ECO treated with IL-17A. The intensity of the color indicates the average expression, and the size of the circle indicates the percentage of cells expressing each gene. DEG were determined by a p-value<0.05 and Log2Fold change > 0.2, and their presence in at least four clusters.
