Figure 6. IL-17A response throughout distinct cholangiocyte cluster populations in non-PSC and PSC ECO.
Volcano plots displaying mRNA expression profiles obtained by NanoString analysis comparing A) vehicle- vs. IL-17A-treated PSC ECO, B) vehicle- vs. IL-17A-treated non-PSC ECO (upregulated genes in green, downregulated genes in black), C) IL-17A-treated PSC vs. non-PSC ECO (upregulated genes in orange, downregulated genes in blue). Each dot represents a gene. Upregulated and downregulated genes are listed next to the volcano plots.
