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[Preprint]. 2023 Oct 18:rs.3.rs-3328953. [Version 1] doi: 10.21203/rs.3.rs-3328953/v1

Figure 12. Optimal pulmonary immune responses to alcohol-associated bacterial pneumonia requires activated AhR and decreased TGF-b signaling.

Figure 12

Pair-fed and alcohol-fed treated with indole, recombinant TGFβ1, anti-TGFβ1, and the AhR antagonist CH223191 were infected with Klebsiella and (A) pulmonary and (B) splenic Klebsiella burden was assessed 48 hrs. post infection; p values are indicated in the figure by one-way ANOVA with Sidak’s multiple comparison. N = 3–8/group.