Single nuclear RNA expression from 4 progressive MS patients and 5 non-neurological controls26 confirms PIGC expression in neuronal and glial cells including oligodendrocyte lineage cells. COPs, committed oligodendrocyte precursors; ImOLGs, immune oligodendroglia; Oligo, oligodendrocyte; OPCs, oligodendrocyte precursor cells; Vasc, vascular.