TABLE 1.
Activity of ABT-378 and ritonavir against wild-type and mutant HIV proteases
| Protease |
Ki (pM)a
|
|
|---|---|---|
| ABT-378 | Ritonavir | |
| Wild type | 1.3 | 10 |
| V82A | 4.9 | 120 |
| V82F | 3.7 | 520 |
| V82T | 3.6 | 300 |
a
Values represent the mean of at least three determinations.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.