Table 3.
Univariate and Multivariate Analyses for Overall Survival in the Propensity Score-matched Cohort.
Univariate analysis | Multivariate analysis | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |||||||||
Age, years | ≥65 | 0.951 | 0.673-1.343 | 0.775 | ||||||||||
Sex | Male | 1.497 | 0.924-2.426 | 0.102 | ||||||||||
ECOG performance status | 1-2 | 1.473 | 1.067-2.034 | 0.019 | 1.414 | 1.012-1.976 | 0.042 | |||||||
Tumor location | Pancreas body-tail | 1.332 | 0.958-1.853 | 0.088 | ||||||||||
Tumor size, mm | ≥30 | 1.128 | 0.801-1.588 | 0.490 | ||||||||||
Stage | UR-M | 1.848 | 1.307-2.612 | 0.001 | 1.807 | 1.111-2.942 | 0.017 | |||||||
Metastatic sites | Lung Liver Peritoneum |
0.813 1.928 0.961 |
0.420-1.574 1.377-2.699 0.608-1.521 |
0.540 0.000 0.866 |
1.103 | 0.688-1.769 | 0.683 | |||||||
Number of metastatic sites | ≥3 | 3.587 | 1.032-12.467 | 0.044 | 3.355 | 0.931-12.084 | 0.064 | |||||||
CRP/Alb | ≥0.18 | 1.296 | 0.936-1.795 | 0.119 | ||||||||||
NLR | ≥5 | 1.299 | 0.860-1.961 | 0.213 | ||||||||||
PLR | ≥150 | 0.921 | 0.667-1.272 | 0.618 | ||||||||||
m-GPS | 1-2 | 2.816 | 1.968-4.029 | 0.000 | 2.698 | 1.855-3.923 | 0.000 | |||||||
PNI | ≥45 | 0.936 | 0.679-1.291 | 0.688 | ||||||||||
CEA, ng/mL | ≥5 | 1.368 | 0.989-1.891 | 0.058 | ||||||||||
CA19-9, UI/mL | ≥37 | 1.217 | 0.798-1.858 | 0.362 | ||||||||||
BMI, kg/m2 | ≥25 | 0.394 | 0.192-0.809 | 0.011 | 0.499 | 0.232-1.074 | 0.075 | |||||||
Sarcopenia | Yes | 0.935 | 0.680-1.286 | 0.680 |
HR: hazard ratio, CI: confidence interval, CRP: C-reactive protein, NLR: neutrophil/lymphocyte ratio, PLR: platelet/lymphocyte ratio, m-GPS: modified Glasgow prognostic score, PNI: prognostic nutritional index, CA19-9: carbohydrate antigen 19-9, CEA: carcinoembryonic antigen, BMI: body mass index, SMI: skeletal muscle index