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. 2023 Sep 21;24(11):1825–1838. doi: 10.1038/s41590-023-01631-w

Extended Data Fig. 2. Gene-by-environment control of macrophage transcription.

Extended Data Fig. 2

a, Global comparison of differentially expressed genes between Kupffer cells or bone marrow-derived macrophages (BMDMs) of the indicated strain. Data represent the row z-score of log2(tpm + 1) values. b, Gene clusters identified in a. Data were subjected to Gene ontology analysis using Metascape. Data indicate the log10(p-value). c,e, Global comparison of strain-specific gene expression only in BMDMs, as in a. d,f, Metascape analysis of results from c and e, as assessed in b. Gene lists for individual clusters a, c and e are provided in Supplemental Table 1.