FIG. 2.

Stability of the fluconazole-resistant phenotype. A clone of the Fluc^r parasite line was inoculated into an untreated mouse and was then recovered from blood after 2 weeks. After expansion in vitro (in the absence of fluconazole), the clone (▴) was tested for its susceptibility to fluconazole. It was compared to Fluc^r parasites which were passaged continuously in vitro in the presence of fluconazole (•) and to the parent line of T. cruzi (■). The experiment has been repeated with three separate mice with similar results.