Table 3.

Mouse acute oral toxicity study with target dose 5000 mg PMI/kg body weight: Mean mouse body weights (g ± SD)

Treatment	n	Days Relative to Start Date
		Day 1a	Day 2	Day 3	Day 5	Day 8	Day 15
Males
Vehicle	6	31.1 ± 2.2	31.7 ± 2.1	31.8 ± 2.0	32.3 ± 2.4	33.0 ± 2.4	34.7 ± 2.5
BSA	6	31.2 ± 1.7	32.1 ± 2.1	31.1 ± 1.8	31.9 ± 1.8	32.4 ± 1.8	34.8 ± 2.1
PMI	6	31.5 ± 2.2	32.7 ± 1.9	31.6 ± 1.9	31.9 ± 2.2	32.5 ± 2.5	35.3 ± 2.4
Females
Vehicle	6	25.1 ± 1.8	25.3 ± 1.9	24.4 ± 1.8	25.3 ± 2.1	26.1 ± 1.3	28.9 ± 1.8
BSA	6	24.0 ± 2.7	24.8 ± 2.4	24.4 ± 2.6	24.7 ± 2.7	25.2 ± 2.5	28.0 ± 2.4
PMI	6	24.8 ± 2.4	24.9 ± 2.5	24.2 ± 2.4	25.1 ± 2.2	25.7 ± 3.0	27.8 ± 1.9

^aFasted weight