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. 2023 Aug 16;149(16):14641–14655. doi: 10.1007/s00432-023-05256-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — The clinicopathological significance of GPR176 protein expression in oesophageal cancer. Western blotting was used to determine the level of GPR176 protein in oesophageal cancer (A). Densitometric analysis showed no difference in GPR176 expression between oesophageal cancer and normal tissues (A, p > 0.05). Immunohistochemically, there was positivity for GPR176 protein expression in oesophageal squamous cancer and epithelial and cancer cells (B). Kaplan–Meier curves and log-rank test were used to clarify the prognostic significance of GPR176 protein expression (C). N normal, T tumor, ns not significant, HR hazard ratio