Table 3.
The relationship between GPR176 protein expression and clinicopathological characteristics of oesophageal cancer by immunohistochemistry
| Clinicopathological features | n | GPR176 expression | PR (%) | ρ | p value | |||
|---|---|---|---|---|---|---|---|---|
| − | + | ++ | +++ | |||||
| Sex | − 0.038 | 0.498 | ||||||
| Female | 46 | 8 | 23 | 8 | 7 | 82.6 | ||
| Male | 276 | 58 | 136 | 52 | 30 | 79.0 | ||
| Age (years) | 0.086 | 0.125 | ||||||
| < 65 | 189 | 40 | 99 | 35 | 15 | 78.8 | ||
| ≥ 65 | 132 | 26 | 60 | 24 | 22 | 80.3 | ||
| Histological grade | − 0.128 | 0.046 | ||||||
| I–II | 199 | 37 | 94 | 41 | 27 | 81.4 | ||
| III | 43 | 13 | 21 | 5 | 4 | 69.8 | ||
| T staging | − 0.026 | 0.651 | ||||||
| T1 | 21 | 2 | 14 | 4 | 1 | 90.5 | ||
| T2 | 58 | 10 | 28 | 15 | 5 | 82.8 | ||
| T3 | 224 | 51 | 111 | 36 | 26 | 77.2 | ||
| T4 | 13 | 3 | 4 | 3 | 3 | 76.9 | ||
| N staging | − 0.015 | 0.794 | ||||||
| N0 | 139 | 25 | 75 | 30 | 9 | 82.0 | ||
| N1 | 95 | 14 | 46 | 17 | 18 | 85.3 | ||
| N2 | 70 | 22 | 30 | 9 | 9 | 82.9 | ||
| N3 | 13 | 3 | 5 | 4 | 1 | 76.9 | ||
| AJCC staging | − 0.008 | 0.888 | ||||||
| I | 18 | 3 | 12 | 3 | 0 | 83.3 | ||
| II | 128 | 20 | 70 | 26 | 12 | 84.4 | ||
| III | 162 | 40 | 70 | 29 | 23 | 75.3 | ||
| IV | 5 | 1 | 3 | 0 | 1 | 80.0 | ||
PR positive rate