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. 2023 Apr 9;39(11):1623–1637. doi: 10.1007/s12264-023-01055-4

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© Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 7 — Summary of complement and coagulation pathway proteins associated with ASD identified in previous studies and this study. A Complement activation pathways and complement-related proteins associated with ASD. Red and pink mark DEPs, of which the red targets are 12 DEPs as potential markers. We compared the protein expression of the complement system in the brain and plasma in other articles. ↑ red, increased protein activity or expression in blood from patients; ↓ red, decreased protein activity or expression in blood from patients; ↑ black, increased RNA expression in brain tissue from patients; ↓ black, decreased RNA expression in brain tissue from patients. B Blood coagulation pathway and coagulation-related proteins associated with ASD.