. 2023 Oct 26;13:18380. doi: 10.1038/s41598-023-45144-w

Table 2.

Percentage of 5-mC level in CRC cell lines growing in 2D and 3D culture models and corresponding FFPE blocks of patients with CRC cancer. Results represent mean ± standard deviation of three independent experiments (n = 3).

Sample	Mean 5-mC% ± SD	Sig	p value
2D	19.10 ± 7.38^a	**	< 0.0001
3D	7.07 ± 3.11^b
FFPE	4.41 ± 3.32^b

FFPE: Formalin-Fixed Paraffin-Embedded; 2D: Two- Dimensional; 3D: Three- Dimensional; 5-mC: 5-methylcytosine. ** p < 0.01. Different letters (a and b) are significant at p < 0.01.