TABLE 2.
Features Identified Using Volcano Plot
| FC | log2(FC) | P adjusted | |
|---|---|---|---|
| Saccharopine | 9.7682 | 3.2881 | 3.26E-09 |
| Phosphocreatine | 6.6061 | 2.7238 | 1.79E-08 |
| Oxalic acid | 5.712 | 2.514 | 1.83E-08 |
| N-Acetyl-L-Aspartic acid | 9.5305 | 3.2525 | 4.86E-07 |
| DDHAP/Glyceraldehyde-3-P | 14.629 | 3.8707 | 4.97E-06 |
| N-Acetyl-L-Glutamic acid | 30.419 | 4.9269 | 0.001316 |
| Glutathione Disulfide | 6.2175 | 2.6363 | 0.002445 |
| N-Acetyl-L-Glutamine | 3.7046 | 1.8893 | 0.008206 |
| Indole-3-propionic acid | 0.39818 | −1.3285 | 0.019883 |
| Allantoin | 0.38598 | −1.3734 | 0.027868 |
| Xanthosine | 0.35625 | −1.489 | 0.03347 |
Metabolites of subjects with postoperative delirium (POD) and those without POD were compared using cutoff: fold-of-change (FC) 2.5, and adjusted P value 0.05 (P value adjusted for repetitive measurements). A total of 11 molecules were differentially abundant between the 2 groups: 3 were decreased in the POD group (FC less than 1), whereas 8 were increase in the POD group.