Comparison 2. Timolol versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Systolic blood pressure	1		Mean Difference (Fixed, 95% CI)	Subtotals only
1.1 30 mg/day	1	20	Mean Difference (Fixed, 95% CI)	‐14.4 [‐21.53, ‐7.27]
2 Diastolic blood pressure	1		Mean Difference (Fixed, 95% CI)	Subtotals only
2.1 30 mg/day	1	20	Mean Difference (Fixed, 95% CI)	‐13.50 [‐18.05, ‐8.95]
3 Heart rate	1		Mean Difference (Fixed, 95% CI)	Subtotals only
3.1 30 mg/day	1	20	Mean Difference (Fixed, 95% CI)	‐16.0 [‐18.88, ‐13.12]
4 Pulse pressure	1		Mean Difference (Fixed, 95% CI)	Subtotals only
4.1 30 mg/day	1	20	Mean Difference (Fixed, 95% CI)	‐0.9 [‐8.70, 6.90]