Oh 1985.

Methods	Randomized, double‐blind, placebo‐controlled, cross‐over study. After 2 weeks of washout, participants were randomized to treatment or placebo for 4 weeks
Participants	15 Chinese participants Mean age (range): 39.3 years (23‐57) Inclusion criteria: BP > 144/94 but < 200/115 mmHg
Interventions	Propranolol 160 mg once daily, propranolol 320 mg once daily, placebo
Outcomes	Resting, exercise and after exercise SBP, DBP, HR, adverse effects
Notes	There were 4 groups (A, B, C, D); however, only group A data were reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No information
Allocation concealment (selection bias)	Unclear risk	No information
Blinding (performance bias and detection bias) All outcomes	High risk	Double dummy, but decreased pulse rate would unblind BP measurement
Incomplete outcome data (attrition bias) Primary and secondary outcomes	Unclear risk	No information
Selective reporting (reporting bias)	High risk	WDAE not reported