Figure 3. Screening Performance Through the US Preventive Services Task Force (USPSTF) 2021 and the Risk-Based Screening (Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial 2012 [PLCOm2012]-Update 6-Year Risk ≥1.3%) Criteria.

In the risk-based screening criteria, participants are eligible for screening if their predicted 6-year risk of lung cancer using the PLCOm2012-Update equals or exceeds the risk threshold (≥1.3%). A, Screening efficiency performance was quantified by screening sensitivity (the number of screening-eligible participants among lung cancer cases). B, Specificity (the number of screening-ineligible participants among non–lung cancer cases). C, The number needed to screen (NNS) to detect 1 lung cancer (the total number of screening-eligible cases divided by the number of screening-eligible lung cancer cases).