Table 2.
Pros and cons of various mobilization methods
| Pros | Cons |
|---|---|
| Chemotherapy + G-CSF | |
| Sufficient collection in 1 session in most patients (depending on collection targets) | Need for hospitalization (depending on the regimen used) |
| Potential need for transfusions | |
| Potential impact on the quality of life | |
| More CD34+ cells | Less lymphocytes |
| Do not improve the control of MM or outcome | |
| G-CSF alone | |
| Easy outpatient procedure | May need more aphereses |
| Cheaper (depending on the need of PLER) | More need for PLER use |
| PLER | |
| Improves CD34+ cell yield | Expensivea |
| Improves lymphocyte yield | |
aUnless generic preparation is available.