Table 2.

Shared under- and overabundant DAPs between LV and IVS tissues. The total number of shared DAPs between LV and IVS tissues are presented for each group comparison. * Under-/overabundance was assigned respective to the asterisk-marked groups in the comparison column. Abbreviations: HCM = hypertrophic cardiomyopathy, DAP = differentially abundant peptide(s), LV = left ventricle, IVS = interventricular septum.

Comparison	Underabundant	Overabundant
Low-Dose * vs. HCM	ACOT4, AFM, ALDH1A1, APOA1, APOA4, AS3MT, C3, C5, CES2, CES5A, CLU, COL28A1, CP, CPN2, CRP, CTSD, EPHX2, F13A1, FUOM, GSTK1, GSTP1, HP, HYI, IGHM, IGLL5, ITIH2, JCHAIN, KNG1, MDH1, MIA3, MYBPC3, NOL3, PON1, PSAP, S100A1, SERPINB2, SERPIND1, SERPING1 (n = 38)	ABCC9, AGK, ANKRD2, AP1G1, APEX1, ATP2B4, BANF1, BCKDK, BDH1, BPHL, CAMK2A, CAVIN4, CD59, CD9, CLPX, COBL, COL15A1, DDRGK1, DNAJB4, DNAJC11, DPYSL3, EIF3H, EIF3I, EIF4A3, ENAH, EPB41L3, FBLN5, FHL1, FLII, FLNC, H1-0, H1-4, H2AX, H2B, H3F3A, HNRNPA3, HNRNPR, HNRNPUL2, HP1BP3, HSPG2, HYOU1, IDH3B, ITIH3, LAMA2, LAMA4, LAMA5, LAMB1, LIMS1, LIPA, LMNB1, LMO7, LOC101083645, MACF1, MACROH2A1, MAPT, METTL7A, MLF1, MTFR1L, MVP, MYADM, MYO18A, MYO1B, NDEL1, NDRG1, NEXN, NID2, NONO, NRAP, NUDT21, PALLD, PARP1, PARVA, PPM1K, PPP2R5A, PTGFRN, PXN, RAP2C, RBMXL1, RPL10A, RPL13, RPL14, RPL15, RPL22, RPL23, RPL24, RPL27A, RPL30, RPL4, RPS18, RPS21, RPS23, RPS24, RPS6, RPS6KA3, RRAD, SLC2A1, SNRPD1, SNRPE, SORBS1, SORBS2, SRSF1, SUN2, SYNPO, SYNPO2L, TGFBI, TLN2, TOMM20, TRIM54, U2AF1, XIRP1, XIRP2 (n = 111)
High-Dose * vs. HCM	AS3MT, CLU, CPT2, CTSD, GPD1L, GSTO1, IGLL5, ITIH2, KNG1, NCEH1, PSAP, S100A1, SERPINB2 (n = 13)	ADSL, ANKRD1, ANXA7, ARPC2, BANF1, CD81, CKAP4, CLPX, COBL, COL15A1, COL18A1, COPB1, COPG1, CTNNA2, DAG1, DNAJA1, DSC2, DSG2, DYNC1LI2, EIF3D, EPB41L2, ERP29, FARSB, FHL1, FLII, FLOT1, GTF2I, H1-10, H1-4, H2B, H3F3A, HNRNPA1, HNRNPA3, HNRNPF, HNRNPL, HNRNPM, HNRNPUL2, HSPB3, HSPG2, HYOU1, IDH3B, ILF2, KIF13B, LGALS3, LMNB1, LYPLA1, MACF1, MCAM, METTL7A, MRPL39, MTFR1L, MVP, MYADM, NARS1, NDEL1, NDUFAF2, NEXN, NONO, NRAP, PARVA, PCYOX1, POGLUT3, PPIB, PRPF8, PTGFRN, PXN, RPL10, RPL14, RPL15, RPL22, RPL24, RPL7A, RPS11, RPS12, RPS23, RPS24, RPS28, RPS3A, RPS6, RRAD, RTN4, RUVBL2, SAE1, SDCBP, SEC22B, SERBP1, SNRPD1, SORBS1, SRI, SRSF1, STBD1, SUCLG2, SUN2, SVIL, SYNCRIP, SYNPO2L, TMED2, TRIM54, U2AF1 (n = 99)
All Doses * vs. HCM	AFM, APOA1, APOA4, AS3MT, ATPAF1, CES5A, CLPTM1, CLU, COL28A1, CP, CTSD, F13A1, FUOM, GPD1L, GSTK1, GSTP1, HP, IGHM, IGLL5, ITIH2, JCHAIN, KNG1, MDH1, MYBPC3, NNMT, PON1, PSAP, S100A1, SERPINB2 (n = 29)	ABCC9, ABLIM1, AGK, AGRN, ANKRD1, ANKRD2, ANXA7, APEX1, ATP2B4, BANF1, BCKDK, BPHL, CA3, CAMK2A, CAPG, CAVIN4, CD44, CD59, CD81, CD9, CKAP4, CLPX, COBL, COL15A1, COL18A1, COL4A1, COL4A2, COL6A1, COL6A2, COMTD1, COPB1, CSPG4, CTNNA1, CTNNA2, CYB5A, DAG1, DDRGK1, DHX9, DNAJB4, DNAJC11, DNAJC8, DPYSL3, DSG2, DYNC1LI2, ECHDC3, EFEMP1, ENAH, EPB41L2, EPB41L3, FAH, FARSB, FBLN5, FBN1, FHL1, FLII, FLOT1, GNB1, GNG12, H1-0, H1-10, H1-4, H2A, H2AX, H2B, H3F3A, HACD1, HDAC2, HMGB1, HNRNPA1, HNRNPA3, HNRNPAB, HNRNPR, HNRNPUL2, HP1BP3, HSPB3, HSPG2, HYOU1, IDH3B, ILF2, ITGA7, KIF13B, KTN1, LAMA4, LAMA5, LAMB1, LDB3, LGALS3, LMNB1, LMO7, LOC101083645, LYPLA1, MACF1, MACROH2A1, MAP1B, MAPT, MCAM, METTL7A, MLF1, MLIP, MOCS1, MSI2, MSN, MTFR1L, MVP, MYADM, MYO1B, MYO1D, NARS1, NDEL1, NDUFAF2, NDUFV3, NES, NEXN, NFIA, NIBAN1, NID2, NONO, NRAP, OBSL1, OMA1, PARP1, PARVA, PCYOX1, PDLIM3, PLGRKT, PLN, POGLUT3, POSTN, PPIB, PPM1B, PPP2R5A, PRNP, PRPF8, PTBP1, PTGFRN, PXN, RAP2C, RBM39, RBMXL1, RPL10, RPL10A, RPL14, RPL15, RPL18, RPL22, RPL23A, RPL24, RPL27A, RPL30, RPL31, RPL39, RPL7A, RPS11, RPS12, RPS15, RPS15A, RPS21, RPS23, RPS24, RPS6, RPS6KA3, RPS8, RRAD, RRBP1, RUVBL2, SAFB, SDCBP, SEMA3C, SERBP1, SF1, SLC2A1, SNRNP70, SNRPD1, SNRPE, SORBS1, SORBS2, SORT1, SRSF1, SSPN, STBD1, SUN2, SVIL, SYNCRIP, SYNPO, SYNPO2L, TGFBI, TIMM29, TINAGL1, TLN2, TMED2, TNKS1BP1, TNXB, TOMM20, TRIM54, TRIM63, TRIP6, TUBB, TXNDC5, U2AF1, USP28, VASP, VCAN, VNN1, XIRP1, XIRP2, YBX1 (n = 206)
Low- * vs. High-Dose	- (n = 0)	- (n = 0)