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. 2023 Oct 12;13(20):3184. doi: 10.3390/ani13203184

Table 3.

Congruent transcript and protein expression of differentially expressed genes/peptides in LV and IVS tissues. The total number of genes/peptides congruently differentially expressed in LV and IVS tissues are presented for each group comparison. Bolded gene symbols represent shared genes/peptides between LV and IVS tissues. * Under-/overabundance was assigned respective to the asterisk-marked groups in the comparison column. Abbreviations: HCM = hypertrophic cardiomyopathy, LV = left ventricle, IVS = interventricular septum.

Comparison LV IVS
Underexpression Overexpression Underexpression Overexpression
Low-Dose * vs. HCM CES2, SERPINB2
(n = 2)
(n = 0)
ANKRD1, ANKRD2, ASPN, DPYSL3, FBLN5, FHL1, LYPLA1, MSN, MYL1, PTGFRN, TGFBI, XIRP2
(n = 12)
(n = 0)
-
(n = 0)
(n = 0)
-
(n = 0)
(n = 0)
High-Dose * vs. HCM AS3MT, PHOSPHO1
(n = 2)
(n = 0)
-
(n = 0)
(n = 0)
-
(n = 0)
(n = 0)
-
(n = 0)
(n = 0)
All Doses * vs. HCM -
(n = 0)
(n = 0)
ASPN, COL6A3, FBLN5, TGFBI
(n = 4)
(n = 1)
-
(n = 0)
(n = 0)
FBLN5
(n = 1)
(n = 1)
Low- * vs. High-Dose -
(n = 0)
(n = 0)
-
(n = 0)
(n = 0)
-
(n = 0)
(n = 0)
-
(n = 0)
(n = 0)