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. Author manuscript; available in PMC: 2023 Oct 27.
Published in final edited form as: Nat Biotechnol. 2022 Jun 13;40(11):1680–1689. doi: 10.1038/s41587-022-01347-6

Fig. 3 |. TACT assays are concordant with gold standard ELLA and ELISpot assays.

Fig. 3 |

a–d, Concordance between assays to quantify cellular immunity. The quantification shown is with the DMSO control subtracted from the spike peptide-stimulated sample. Each dot represents a unique participant color coded based on their COVID-19 and vaccination statuses (legend). The dashed line represents thresholds for each assay. a, Concordance between ELLA and qTACT assays. For 117 participants, IFN-γ protein secretion was quantified by ELLA (y axis) and CXCL10 mRNA by qTACT (x axis). b, Concordance between ELLA and dqTACT assays. For 133 participants, IFN-γ protein secretion was quantified by ELLA (y axis) and CXCL10 mRNA by dqTACT (x axis). c, Concordance between ELISpot and qTACT assays. For 50 participants, IFN-γ producing cells were quantified by ELISpot (y axis) and CXCL10 mRNA by qTACT (x axis). d, Concordance between ELISpot and dqTACT assays. For 46 participants, IFN-γ producing cells were quantified by ELISpot (y axis) and CXCL10 mRNA by dqTACT (x axis).