Table 1.

Comparison between human symptoms and animal models.

Symptoms in Humans		Behavioral Test	Main Parameters in Rodents	References
Impaired social interaction		Three-chamber sociability test	Time and fr. near stimulus animal	[70]
		Social interaction test	Time and fr. of social interactions
Deficient communication		MS-USV	USV	[71]
Repetitive behavior		MBT	Number of buried marbles, time of digging	[73]
		Self-grooming	Grooming time and fr. in OFT	[74]
Comorbidity	Motor functions	Rotarod	Latency to fall	[75]
		Erasmus Ladder	Number of missteps	[76]
		DigiGait	Stance stride length and steps/sec	[77]
		Delay eyeblink conditioning test	Successful conditioned response, blink amplitude and blinking speed	[77]
	Anxiety	OFT	Total distance, time in center	[72]
		EPM	Time and fr. in arms	[72]
	Pain sensitivity	Hot plate test	Withdraw latency	[78]
		Tail flick test	Withdraw latency	[78]

Abbreviations: EPM: elevated plus maze; fr.: frequency; MBT: marble burying test; MS-USV: maternal separation-induced ultrasonic vocalization; OFT: open-field test; USV: ultrasonic vocalization.