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Effects of blocking the opioid receptors µ (naloxone, 5 mg, IP), δ (naltrindole 1 mg, IP), and κ (Nor-BNI, 1 mg, IP), on the antinociception of phosphonate valorphin analog (V2p, 25 µg, ICV) in acute (A) and inflammatory phases (B) of formalin test in mice. Data show the mean ± SD; n = 8. * p < 0.05 vs. controls treated ICV with saline and injected SC with formalin.
