Table 3.
Association of different comorbidities with an increased nocturnal hypoxemic burden using multivariable linear regression.
| Adjusted for Age and Sex | Adjusted for Age, Sex, and All Independent Variables | ||||
|---|---|---|---|---|---|
| B (95% CI) | p-Value | B (95% CI) | p-Value | ||
| Dependent Variable: T90/TRT | |||||
| independent variables | Sleep-disordered breathing (AHI ≥ 15/hour) | 9.7 (5.4; 14.0) | <0.001 | 6.5 (0.4; 12.5) | 0.036 |
| Heart failure | 6.3 (0.7; 11.8) | 0.027 | 3.8 (−3.0; 10.6) | 0.273 | |
| Obesity | 9.9 (5.4; 14.3) | <0.001 | 8.2 (2.5; 13.9) | 0.005 | |
| Mild-to-moderate chronic obstructive pulmonary disease | 18.6 (11.3; 25.9) | <0.001 | 16.7 (8.5; 25.0) | <0.001 | |
| Dependent Variable: T90desaturation/TRT | |||||
| independent variables | Sleep-disordered breathing (AHI ≥ 15/hour) | 10.0 (8.3; 11.6) | <0.001 | 8.4 (6.1; 10.7) | <0.001 |
| Heart failure | 6.3 (4.0; 8.7) | <0.001 | 3.7 (1.1; 6.4) | 0.006 | |
| Obesity | 5.3 (3.4; 7.2) | <0.001 | 2.9 (0.7; 5.1) | 0.010 | |
| Mild-to-moderate chronic obstructive pulmonary disease | 4.3 (1.1; 7.5) | 0.008 | 3.6 (0.4; 6.8) | 0.026 | |
| Dependent Variable: T90non-specific/TRT | |||||
| independent variables | Sleep-disordered breathing (AHI ≥ 15/hour) | 1.1 (−2.7; 5.0) | 0.559 | −1 (−6.6; 4.5) | 0.712 |
| Heart failure | 0.8 (−4.1; 5.7) | 0.756 | 0.05 (−6.2; 6.3) | 0.988 | |
| Obesity | 6.3 (2.3; 10.2) | 0.002 | 7.1 (1.9; 12.2) | 0.008 | |
| Mild-to-moderate chronic obstructive pulmonary disease | 17.7 (11.2; 24.2) | <0.001 | 17 (9.5; 24.6) | <0.001 | |
B: beta coefficient and 95% CI: confidence interval. AHI: apnea–hypopnea index; TRT: artifact-free total recording time.