Table 4.
Total protein content, catalytic activities of enzymes, and concentrations of antioxidant markers in rat liver exposed to different doses of YY and CCP EO co-administered with CCl4.
| Group |
rTP (g/L) |
rTBARS (nmol/mg) |
rSOD (U/mg) |
rCAT (U/mg) |
rGSH (mg/g) |
|---|---|---|---|---|---|
| I | 5.56 ± 0.14 a† | 2.48 ± 0.02 † | 5.27 ± 0.95 † | 120.87 ± 0.15 † | 32.24 ± 0.12 † |
| II | 6.97 ± 0.12 * | 4.40 ± 0.14 * | 2.76 ± 0.36 * | 70.10 ± 0.3 * | 14.62 ± 0.16 * |
| III | 18.94 ± 0.17 *† | 1.84 ± 0.08 *† | 4.95 ± 0.74 *† | 78.93 ± 0.08 *† | 15.76 ± 0.20 *† |
| IV | 15.82 ± 0.23 *† | 0.84 ± 0.09 *† | 5.07 ± 0.63 *† | 113.24 ± 0.10 *† | 16.96 ± 0.12 *† |
| V | 12.90 ± 0.34 *† | 0.66 ± 0.08 *† | 5.15 ± 0.69 *† | 118.15 ± 0.15 *† | 20.26 ± 0.13 *† |
| VI | 8.07 ± 0.24 *† | 2.01 ± 0.02 *† | 4.83 ± 0.44 *† | 73.47 ± 0.23 *† | 17.15 ± 0.14 *† |
| VII | 14.56 ± 0.17 *† | 0.94 ± 0.03 *† | 5.11 ± 0.78 *† | 111.76 ± 0.22 *† | 21.62 ± 0.02 *† |
| VIII | 14.14 ± 0.41 *† | 0.22 ± 0.06 *† | 5.24 ± 0.85 † | 118.87 ± 0.11 *† | 29.32 ± 0.18 *† |
a Values represent mean ± SEM from three independent experiments; n = 5 rats per group; I—Negative control, 1 mL/kg bwt olive oil, i.p.; II—Positive control, 1 mL/kg bwt of CCl4, 1:1 mixture in olive oil, i.p.; III—1 mg/kg bwt of YY EO + 1 mL/kg bwt of CCl4, i.p.; IV—200 mg/kg bwt of YY EO + 1 mL/kg bwt of CCl4, i.p.; V—400 mg/kg bwt of YY EO + 1 mL/kg bwt of CCl4, i.p.; VI—1 mg/kg bwt of CCP EO + 1 mL/kg bwt of CCl4, i.p.; VII—200 mg/kg bwt of CCP EO + 1 mL/kg bwt of CCl4, i.p.; VIII—400 mg/kg bwt of CCP EO + 1 mL/kg bwt of CCl4, i.p.; * p < 0.05 when compared with the negative control group; † p < 0.05 when compared with the positive control group.