Table 6.
Total protein content, catalytic activities of enzymes, and concentrations of antioxidant markers in rat kidneys exposed to different doses of YY EO, CCP EO, and CCl4.
| Group |
rTP (g/L) |
rTBARS (nmol/mg) |
rSOD (U/mg) |
rCAT (U/mg) |
rGSH (mg/g) |
|---|---|---|---|---|---|
| I | 3.91 ± 0.14 a† | 0.43 ± 0.02 † | 5.11 ± 0.32 † | 170.78 ± 0.15 † | 39.58 ± 0.12 † |
| II | 5.78 ± 0.12 * | 1.74 ± 0.14 * | 3.12 ± 0.43 * | 52.54 ± 0.3 * | 19.67 ± 0.16 * |
| III | 3.96 ± 0.17 † | 3.85 ± 0.08 *† | 4.26 ± 0.23 *† | 147.05 ± 0.08 *† | 24.64 ± 0.20 *† |
| IV | 2.59 ± 0.23 *† | 3.72 ± 0.09 *† | 4.44 ± 0.25 *† | 166.27 ± 0.10 *† | 31.78 ± 0.12 *† |
| V | 3.22 ± 0.34 *† | 1.23 ± 0.08 *† | 5.49 ± 0.69 *† | 168.98 ± 0.15 *† | 37.18 ± 0.13 *† |
| VI | 3.16 ± 0.24 *† | 2.77 ± 0.02 *† | 4.12 ± 0.32 *† | 152.46 ± 0.23 *† | 21.20 ± 0.14 *† |
| VII | 5.76 ± 0.17 * | 2.73 ± 0.03 *† | 4.32 ± 0.34 *† | 164.16 ± 0.22 *† | 27.83 ± 0.02 *† |
| VIII | 4.64 ± 0.41 *† | 1.09 ± 0.06 *† | 5.85 ± 0.85 *† | 165.52 ± 0.11 *† | 39.22 ± 0.18 † |
a Values represent mean ± SEM from three independent experiments; n = 5 rats per group; I—Negative control, 1 mL/kg bwt olive oil, i.p.; II—Positive control, 1 mL/kg bwt of CCl4, 1:1 mixture in olive oil, i.p.; III—1 mg/kg bwt of YY EO + 1 mL/kg bwt of CCl4, i.p.; IV—200 mg/kg bwt of YY EO + 1 mL/kg bwt of CCl4, i.p.; V—400 mg/kg bwt of YY EO + 1 mL/kg bwt of CCl4, i.p.; VI—1 mg/kg bwt of CCP EO + 1 mL/kg bwt of CCl4, i.p.; VII—200 mg/kg bwt of CCP EO + 1 mL/kg bwt of CCl4, i.p.; VIII—400 mg/kg bwt of CCP EO + 1 mL/kg bwt of CCl4, i.p.; * p < 0.05 when compared with the negative control group; † p < 0.05 when compared with the positive control group.