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Schematic representation of mitochondrial stress-induced inflammatory response and cell death. TLR4s—toll-like receptors 4; ETC—electron transport chain; IFNs—interferons; IL-6—interleukin 6; TNF—tumor necrosis factor; IFN β1—interferon beta 1; IL-1β—interleukin 1 beta; IRF—interferon regulatory factor; NFκB—nuclear factor kappa beta.
