Summary of findings 1. Single‐incision slings compared to autologous fascial slings for urinary incontinence in women.
| Single‐incision slings (excluding TVT‐S) compared to autologous fascial slings for urinary incontinence in women | ||||||
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Patient or population: women with urinary incontinence Settings: secondary care Intervention: single‐incision slings (excluding TVT‐S) Comparison: autologous fascial slings | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | № of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| Autologous fascial sling | Single‐incision slings (excluding TVT‐S) | |||||
| Subjective cure or improvement of urinary incontinence: at 12 months | ‐ | ‐ | ‐ | ‐ | ‐ | Not reported |
| Patient‐reported pain: at more than 24 months | ‐ | ‐ | ‐ | ‐ | ‐ | Not reported |
| Number of women with dyspareunia | Study population | RR 1.33 (95% CI 0.32 to 5.53) |
70 (1 study) |
⊕⊕⊝⊝ Lowa |
‐ | |
| 86 per 1000 | 114 per 1000 (27 to 474) |
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| Number of women with mesh exposure, extrusion or erosion in any area | Study population | RR 2.00 (95% CI 0.19 to 21.06) |
70 (1 study) |
⊕⊕⊝⊝ Lowa |
‐ | |
| 29 per 1000 | 57 per 1000 (5 to 602) |
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| Number of women with urinary retention | ‐ | ‐ | ‐ | ‐ | ‐ | Not reported |
| Quality of life: at 12 months | ‐ | ‐ | ‐ | ‐ | ‐ | Not reported |
| Number of women requiring repeat continence surgery | ‐ | ‐ | ‐ | ‐ | ‐ | Not reported |
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval; RR: risk ratio; TVT‐S: tension‐free vaginal tape‐Secur | ||||||
| GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect. Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect. Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect. | ||||||
aDowngraded twice for serious imprecision: very wide CIs including both benefit and harm, and one small study with small sample size.