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Schematic diagram of the ketogenic pathway and its regulators. (+), activation; (−), inhibition; βHB, β-hydroxybutyrate; 3-KT, 3-ketothiolase; ACC, acetyl-CoA carboxylase; CPT, carnitine palmitoyltransferase (carnitine shuttle); HMGCS, mitochondrial HMG-CoA synthase; TCA, tricarboxylic acid.
